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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59dcccb3bab08aa275d0635a8ab7f74ed652d97f6783782f9620a0c90d2cc88f' 
  AND token = 'VCRFffd1zmlr/dS5oXCw77+1jtxdmXXrvBVVW8VMb6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}