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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12809ca56b8960d3c8c86ad8fe44da605955a5dde9507377640da44465128a1' 
  AND token = 'kx3oVZtNsZdQmWKorayc/UJ7mUo3cQESM7gjrVTOHqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}