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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e50006c5d65bdf4607c830dc57f6429e97e838cf034f17aadb7eb6fd604d494' 
  AND token = 'toiE3nWFsPyrnJVql85IHKujWmpCA3xqx6gtyFZHP2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}