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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b72b0e9f78958d24fda90b847d3121431a78dc48359f23f715ba8a5ed644b2b' 
  AND token = '7tGEaR6xiaeOZD81izT2dWp5AQhhrZg12/3HJ3gTqcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}