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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaed794b04e080a87a1854f223111096e71cb09a845fb9015fad9549739d7277' 
  AND token = 'EeIDMcVyyksPquxR4Y1wbeyxDN3F0SS+sYKilQ/HONc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}