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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a03f6005e0e20c32805eeda30c7e9dfe9e6450688bb2f7741fe72289ae8d12' 
  AND token = 'TLXInNhIj5VH7ZfkdAW2SxLThAsH93IWZ/TrxMY08GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}