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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742278696e1a63947a14f4c31e01a76f8d86c8c15381806be4c2ee81ddbd62e3' 
  AND token = 'FWPlXZIDbxk4B5qy786JME6RKkbC2qwepPDoav6wc1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}