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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c00f81c7230fc887bbdcd74a9f1e6cf1e392456c8e2f457502c70679080f99' 
  AND token = '6RTOLho+DasSbCkAj9NkI9v59A0rBvPsdshObGyu1bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}