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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8cbe21eb658698891e28f0907da43ce4f94723e8d83f8656498c455e53dacf' 
  AND token = 'TKwmdR8Zl0THKZg/kEVm7SMEXn54YzYdIRe0egbG7vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}