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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1d1c0ca98e36b57233741459e75926320cca6351dd30c7bddb4f90eff0f537' 
  AND token = '0fiXIdTkG3E7tW1RmDE34VrON1QivC1KH7aGUEk96kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}