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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '822d6849ca02b1c2ba7da703d7638d0e81cb55873725d5c1fb67a42f10943d77' 
  AND token = 'FJIW8o0Z1W2QEQuJjirc96RD4I7AoOr8e+M84f9zcmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}