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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c163e1261e9cae125728db8b8513d0ff835a9d5e2675ecc10ade73a9bcd36a17' 
  AND token = 'R/ObLEUmVcW5raco+JeMiJeaNc8aiD1WvCrhMg7EVt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}