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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1453620a801b02898e9003ef37d96be8e7e7638861e25cb8b9d44555aa347344' 
  AND token = 'WdL9Sm87XrbAuCRfpI5+txYw9tE3DP9oFtYNFhz6K4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}