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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c43e96cdcc84d0d60e7f53f5fd0b8b93ab34a0f07e4aeb739f9db9729ef2338' 
  AND token = 'qOgdAoY5V7zsmaHlDU/1k6Za0sksDlIwCbAnNmgCLuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}