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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81512dc66dfed5f0be1b2d35349d4018f4b5e09971b7cd56dbdfbcdff9200f59' 
  AND token = 'mCD/n80mnpOj75R0aD18cewjgL1Z2V6fwkvc1FsPFV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}