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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22016a168f885748c5acfd019a6dbb331a1f586c0f55cbc5123d0b4adc96f2e5' 
  AND token = 'ekWQoc9jQKAnjU2kRhT49weNbxz+OjrMIUOrheT0ynU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}