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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad6d80a414d798b7532559701a1a30ab9941ae7deaf6d2e4afd5ed5b466eb16' 
  AND token = '9CnJQTFXLjXWn/OB+z9A9l8pAGTkePOiR8NEr23oFmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}