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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7368168c79c993724a0897d070f2b019e389220b0e7a0efc8b0cd2566c2781' 
  AND token = '8nVbHD4vBjrLK4QV3+5+WzG8k/No77rlgNZZf+J2QME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}