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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77af4bc7340ff0a2e706174b6201bc81fb46568d3de561b0e1d75799cfa5287a' 
  AND token = 'DHo8AruyopqrfZ1FR08T5f2HZmsruabKDzERNM3FLzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}