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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a9f03156a8bf72038ec5ce958557b868da26227809aad06c7805c2a034c4db' 
  AND token = '3PER/DZuZKBb4eFPevE/lpMwCQMYtfBgk9+0+P2nKyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}