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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bfd13de5b67ac24b9ff2f8dc9e0452797f12722a42e828821d89438e6b23e0e' 
  AND token = 'eKhna4lS1Lcb3w4++iPzqVZjhlTWDEv0zkGT5xHibAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}