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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c421c386928591a4885668b6a2e3d44a186d4941a25123014313b883ee05ae8' 
  AND token = 'wH37FX6vOQtgNrffFOlPFDdjvzGPDGbX09F4qr8mz3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}