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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e1289420ae6eb3b2719a19a6344efb6ce87ed8f78873c0e68a68c4ba21318c' 
  AND token = '777/jgervSSD76IkrpIyeVmbY+WJNiQi/dstmM8Pvrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}