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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59f729871e88353b9c5d0924c4b5593a47108f8d3e92d9989501e005c2e8ba08' 
  AND token = 'tnbiDE5BB+HfYo9vEwhzxTl+sMN3eKO4M5HrGbfWIJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}