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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9fe7f3f39bfb4f7975ac964b432dcd9e4a998decf22f213e08260dd6c6de564' 
  AND token = 'obSFgvx6NS3541LWaDHIeyUL1iiLRR1PJCIt6lX/bIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}