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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b61a15f1b27e75d07540dd918b0560286b89d540407e5bcd3ef7b8b155bf327' 
  AND token = 'tMop7MfLn5CL3ShyZN+D+VozYEMF7TgdymgK17UhhtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}