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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3f843685e8bd2ce2f81b7653db111533c07a4d4700b3d1dec8df4e0c3193b2' 
  AND token = '+IXcy6WBAXV26lE1Njmt6qbAvbX1Z9pXfrg0l42wyz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}