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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8abae760511a29d055f011b2eaed1f8e7bce42050bef69ded1401b56ca7391c' 
  AND token = 'BMu4Kk+HjONl2CJkymqjiJR+XTyYRmCjcNERcwnAafU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}