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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50dddbe3021d4b9ac3ebe97877f8a55d3a2f4385aef18b1ac8d9eff3d538ef71' 
  AND token = 'IUzh/thOQAZZ0IUlS2x3NELk3VKRFMdFRgSNb3wTf28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}