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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cdd462704f4406c8ce3d652d790c6eba6324b2042e4b82d9d582a07df57878d' 
  AND token = '34LIE+b7DOgQE5HeKNWMMH/lzdRBN/DhRHleidD2dyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}