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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225087c89e1ff9f70740882c5fbca0f643dd83c9a621836e2851ddf73feb42f2' 
  AND token = 'Z+DuDBTsS031k3B/MW6eCcJwdWfqfqH6q66fEdG+jls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}