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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a8e3a68d56cba63005524ab4100ce699297e5f55e72b2c86f868711a050614' 
  AND token = 'g2A/X+BITT1Fbos4rKfU1EqB2dA8g1zE3RvvVtysdM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}