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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe9c78ce82101e9f0b2c66b7e4486e8ab67cce60418ebddbf75c389ec105e7a8' 
  AND token = 'UDSoIAVrAQQFia+0TjtRNscMr5nbT+DFldV5B+VNmFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}