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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34ab7e625bed01c3b6e0f4550bce43592e8c0c8e9211ad84010017c3a0d703b4' 
  AND token = 'xwpddCbQ8IcI7n2x/K+XGi0ma/WsiWlZQSqMCDeJ7TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}