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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eadb4b6b1f917891244a529e3e202f95fd2d31d4394033e41d25d374e3421312' 
  AND token = 'FrJgDRM3LZ1ZagrihKHpODS7mfpoz+EvaUj52gS0HVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}