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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afe5d50c8b97927dcd744a9fba02eed743776dd6248712ef67199dd159ac2550' 
  AND token = 'UJYvX76udJ/deCExclgF/TlLgNDXaNDX3EaUnIFK93Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}