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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c23daaa02c15cd947687642738ee1fff6673c9da68dc480b5f914c268f351f' 
  AND token = 'arsR+Nz6Vg3mjpY0sLnXUes3eG7YR3fEpmngsuUR0Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}