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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '610b9165361c8c356dd5ed9344c538b47a8e02117b7daf2f66ba980e3fd5ffac' 
  AND token = 'rFCZipLMkhU142xeObHNc161rgHq4imziFPeWyRmItg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}