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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382feaf9c333b245298bb0d8ca56d060dcd73726acd304f75f0894bcb24c7196' 
  AND token = '5btlGKDI/SAJrvDyq7U3iI/k2dFWoE8pl2hfWXuKuVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}