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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09ab2649e99ea92365d1c91756fddb249a04f5eff694c08b4ed5676e1cf6f143' 
  AND token = 'jr+VdLCK4W71k4dn3KNjNNbW89AopVbFWZpqvj21OKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}