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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cdc64b771ea6d311a3809a5f4ae6f2c14314de73f934132ded1182c08a1d19a' 
  AND token = 'zkcgnAkMAJrEMT9A2FEW4V37GL7BXUGJ48Ud5Y0wkLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}