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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5429f2311fbecc0ad810ffc97622f7335bae7c6961b8dc5bc7c6a640aa36d76' 
  AND token = 'OXm3VWtEiKgdhada2bSQHRUD6+d1HvzwcbPlS3M0ww0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}