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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4286dd4c52b14fb386a679db1595da42c497efcc0494222c501232a76df27037' 
  AND token = 'bTQWLep5Pxwf4IVRMJSc9386ht/cEIvxNlUbVICwhvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}