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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387a93c877fd449f8d892dae4b8421ae0480c8f26fde5a429da59b3979597177' 
  AND token = 'RJd97MmmMzaGEaxPp8+p8DbrL6nJQWARdbwzq2fRmBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}