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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6596f1ad4ff92c2d7beccb0a96622c561eef82075d6b0a597d0c982cba64d2bc' 
  AND token = '6A+kmFSzfuYYDACj8YXjqo5ZIyNNnq1BXnXRLeNcY7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}