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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd019a0a367613251ff1950108b4c4b80db5bd824441b73b22066652ad853d78c' 
  AND token = 'DLw0MoN4+AvSpLXIurd8jcJM2rRkcF2L3R27Swnm3NQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}