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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e291a5bb5d5407630c9d08d9be9e0b8c3a73c89a7d12b8a7315b219ffe4e1b7' 
  AND token = 'lMCnDaCcKa7+fBnLwAOE8nViK+QGSgBYmeo0XLmaBVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}