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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43f2d340dfd92875f8e63e30b5d7f0784096ad0326ef672f5c7dc6fb227fd72' 
  AND token = 'qTQRqkQHuT+Qvj4Y7QiYJRJem7+LwjNOrbyBeunmW10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}