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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7280b5294e60dafbd862f8e2ff39e7ccd7f8791019fc2c2c08607d0aee9a04' 
  AND token = 'N9grkYqYCTWPuSZl9A2h3cgFjfr8VeE8Q7sloyeA2kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}