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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234f4fcbbf98381a88622f6ff35cc7403eb76ce13f39ae50423f80ee4c9dacc0' 
  AND token = 'MI+FEKuCaRKJFUs1pJvamE3Ki7TY53yiq2NJlYVT0Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}